St. Louis Comedy Shows in May 2027

Stand-up comedians, comedy clubs, touring acts, and performances in St. Louis and nearby areas.

Updated: October 15, 2026
2 Comedy Venues

Browse upcoming comedy shows in St. Louis during May 2027. Explore stand-up performances, comedy club events, touring comedians, special appearances, venue information, and ticket options updated regularly.

3
Comedy Shows
May 14
Next Show
$48
Lowest Price
$243
Average Price
Next Comedy Show:
Matt Mathews
May 14 · 7:00 PM · St. Louis, MO
View Tickets
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Comedy Shows Schedule
Featured Comedy Shows
Popular Comedy Venues
About Comedy Shows
Comedy Shows by Month

Comedy Shows by Date

Popular comedians, touring acts, and upcoming comedy performances this month.

Comedy Shows Schedule — May 2027

Upcoming comedy performances, club shows, and touring comedians.
Upcoming Comedy Shows: 3
  • May
    14
    2027
    7:00 PM
    Fri
    COMEDY
    Matt Mathews
    Stifel Theatre • 3,100 seats
    Stifel Theatre
    location1400 Market Street, St. Louis, MO 63103location1400 Market Street, St. Louis, MO 63103
    From $62Avg. price ~ $247Tickets Available: 283
    View Tickets
  • May
    14
    2027
    10:15 PM
    Fri
    COMEDY
    Matt Mathews
    Stifel Theatre • 3,100 seats
    Stifel Theatre
    location1400 Market Street, St. Louis, MO 63103location1400 Market Street, St. Louis, MO 63103
    From $58Avg. price ~ $148Tickets Available: 656
    View Tickets
  • May
    20
    2027
    7:30 PM
    Thu
    COMEDY
    Best Value
    Joe Fenti
    Helium Comedy Club - St. Louis
    Helium Comedy Club - St. Louis
    location1151 St Louis Galleria Street, St. Louis, MO 63117location1151 St Louis Galleria Street, St. Louis, MO 63117
    From $48Avg. price ~ $91Tickets Available: 36
    View Tickets

Featured Comedy Shows in May 2027

Popular comedians, touring acts, and upcoming comedy performances this month
Matt Mathews
Matt Mathews
Stifel Theatre
St. Louis, MO
Upcoming Events 10
Next Event: May 14, 2027 7:00 PM
View Tickets
Joe Fenti
Joe Fenti
Helium Comedy Club - St. Louis
St. Louis, MO
Upcoming Events 1
Next Event: May 20, 2027 7:30 PM
View Tickets

Popular Comedy Venues in St. Louis

Comedy clubs, theaters, casinos, and entertainment venues in St. Louis and nearby areas.
Helium Comedy Club - St. Louis
St. Louis, MO
Comedy Club
Upcoming Comedy Shows: 1
Next Event: May 20, 2027
→
Stifel Theatre
St. Louis, MO
Theatre
Upcoming Comedy Shows: 2
Next Event: May 14, 2027
→
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About Comedy Shows in May

Stand-up comedy, touring comedians, improv shows, and live entertainment.

Comedy events in St. Louis during May 2027 may include stand-up comedy, improv performances, touring comedians, comedy festivals, podcast tours, and live entertainment across venues throughout the region.

Comedy Shows by Month

Browse comedy shows scheduled throughout the year.
January
Comedy Shows in January 2027
2 Upcoming Comedy Shows
February
Comedy Shows in February 2027
15 Upcoming Comedy Shows
March
Comedy Shows in March 2027
5 Upcoming Comedy Shows
April
Comedy Shows in April 2027
15 Upcoming Comedy Shows
May
Comedy Shows in May 2027
3 Upcoming Comedy Shows
June
Comedy Shows in June 2027
Comedy Shows Coming Soon
July
Comedy Shows in July 2027
Comedy Shows Coming Soon
August
Comedy Shows in August 2027
Comedy Shows Coming Soon
September
Comedy Shows in September 2027
Comedy Shows Coming Soon
October
This Month
Comedy Shows in October 2026
21 Upcoming Comedy Shows
November
Comedy Shows in November 2026
48 Upcoming Comedy Shows
December
Comedy Shows in December 2026
22 Upcoming Comedy Shows